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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2006 1
2009 3
2010 1
2012 1
2013 1
2014 2
2015 2
2016 1
2017 2
2019 2
2020 1
2021 2
2023 1
2024 0

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23 results

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Page 1
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.
Remsberg JR, Suciu RM, Zambetti NA, Hanigan TW, Firestone AJ, Inguva A, Long A, Ngo N, Lum KM, Henry CL, Richardson SK, Predovic M, Huang B, Dix MM, Howell AR, Niphakis MJ, Shannon K, Cravatt BF. Remsberg JR, et al. Among authors: firestone aj. Nat Chem Biol. 2021 Aug;17(8):856-864. doi: 10.1038/s41589-021-00785-8. Epub 2021 Apr 29. Nat Chem Biol. 2021. PMID: 33927411 Free PMC article.
Arhgap36-dependent activation of Gli transcription factors.
Rack PG, Ni J, Payumo AY, Nguyen V, Crapster JA, Hovestadt V, Kool M, Jones DT, Mich JK, Firestone AJ, Pfister SM, Cho YJ, Chen JK. Rack PG, et al. Among authors: firestone aj. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11061-6. doi: 10.1073/pnas.1322362111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024229 Free PMC article.
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo.
Randolph JT, O'Connor MJ, Han F, Hutchins CW, Siu YA, Cho M, Zheng Y, Hickson JA, Markley JL, Manaves V, Algire M, Baker KA, Chapman AM, Gopalakrishnan SM, Panchal SC, Foster-Duke K, Stolarik DF, Kempf-Grote A, Dammeier D, Fossey S, Sun Q, Sun C, Shen Y, Dart MJ, Kati WM, Lai A, Firestone AJ, Kort ME. Randolph JT, et al. Among authors: firestone aj. J Med Chem. 2023 Mar 23;66(6):3852-3865. doi: 10.1021/acs.jmedchem.2c01415. Epub 2023 Mar 6. J Med Chem. 2023. PMID: 36877935
Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Sulahian R, Kwon JJ, Walsh KH, Pailler E, Bosse TL, Thaker M, Almanza D, Dempster JM, Pan J, Piccioni F, Dumont N, Gonzalez A, Rennhack J, Nabet B, Bachman JA, Goodale A, Lee Y, Bagul M, Liao R, Navarro A, Yuan TL, Ng RWS, Raghavan S, Gray NS, Tsherniak A, Vazquez F, Root DE, Firestone AJ, Settleman J, Hahn WC, Aguirre AJ. Sulahian R, et al. Among authors: firestone aj. Cell Rep. 2019 Oct 1;29(1):118-134.e8. doi: 10.1016/j.celrep.2019.08.090. Cell Rep. 2019. PMID: 31577942 Free PMC article.
Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Burgess MR, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. Burgess MR, et al. Among authors: firestone aj. Blood. 2014 Dec 18;124(26):3947-55. doi: 10.1182/blood-2014-05-574582. Epub 2014 Oct 31. Blood. 2014. PMID: 25361812 Free PMC article.
23 results